Comparison of Oxidative Stress Parameters in Heart Failure Patients Depending on Ischaemic or Nonischaemic Aetiology

Table 2

Redox biomarkers of patients included into a study with comparison of study groups. Variables are shown as medians with lower and upper quartiles where appropriate.

	Ischaemic ()	Nonischaemic ()	value
TAC (mmol/l)	1,14 (1,04-1,26)	1,11 (0,98-1,22)	0,001
TOS (mmol/l)	4,75 (4-6,1)	5,10 (4,3-6,2)	NS
OSI (TOS/TAC)	4,27 (3,31-5,65)	4,60 (3,68-5,89)	0,01
Uric acid (μmol/l)	407,0 (333,0–505,0)	413,0 (326,0-506,0)	NS
Uric acid (μmol/l) XOi (-)	406,0 (336,0–491,0)	423,5 (344,5–497,5)	NS
Uric acid (μmol/l) XOi (+)	410,5 (324,0–541,0)	403,0 (308,0–519,0)	NS
Bilirubin (μmol/l)	12,70 (9,20-19,10)	15,40 (10,60-21,90)	0,001
Albumin (g/l)	42,00 (39,00–44,00)	42,00 (39,00–45,00)	NS
PSH (μmol/g of protein)	4,10 (3,1-5,1)	4,75 (3,65-5,6)	0,001
MDA (μmol/l)	1,80 (1,40-2,20)	1,70 (1,40-2,10)	0,05
MDA/PSH ratio	0,435 (0,314-0,647)	0,358 (0,269–0,527)	0,001

TAC: total antioxidant capacity; TOS: total oxidant status; OSI: oxidative stress index; MDA: malondialdehyde; PSH: sulfhydryl groups; XOi: xanthine oxidase inhibitors; NS: nonsignificant.