Research Article
Comparison of Oxidative Stress Parameters in Heart Failure Patients Depending on Ischaemic or Nonischaemic Aetiology
Table 3
Correlation between redox parameters and clinical characteristic of heart failure in ischaemic and nonischaemic cardiomyopathy.
| | ICM | nICM | Spearman ; | Spearman ; |
| | NYHA | NYHA | PSH (μmol/g of protein) | ; NS | ; | TAC (mmol/l) | ; NS | ; NS | TOS (mmol/l) | ; | ; | OSI (TOS/TAC) | ; NS | ; NS | MDA (μmol/l) | ; | ; | MDA/PSH ratio | ; NS | ; | Uric acid (μmol/l) (all) | ; | ; NS | Uric acid (μmol/l) XOi (-) | ; | ; NS | Uric acid (μmol/l) XOi (+) | ; NS | ; NS | Bilirubin (μmol/l) | ; | ; | Albumin (g/l) | ; | ; |
| | LVEF | LVEF | PSH (μmol/g of protein) | ; NS | ; NS | TAC (mmol/l) | ; NS | ; NS | TOS (mmol/l) | ; NS | ; NS | OSI (TOS/TAC) | ; NS | ; NS | MDA (μmol/l) | ; NS | ; NS | MDA/PSH ratio | ; NS | ; NS | Uric acid (μmol/l) (all) | ; | ; NS | Uric acid (μmol/l) XOi (-) | ; | ; NS | Uric acid (μmol/l) XOi (+) | ; NS | ; NS | Bilirubin (μmol/l) | ; | ; | Albumin (g/l) | ; | ; NS |
| | NT-proBNP | NT-proBNP | PSH (μmol/g of protein) | ; NS | ; | TAC (mmol/l) | ; NS | ; NS | TOS (mmol/l) | ; NS | ; NS | OSI (TOS/TAC) | ; NS | ; NS | MDA (μmol/l) | ; NS | ; NS | MDA/PSH ratio | ; | ; NS | Uric acid (μmol/l) (all) | ; | ; NS | Uric acid (μmol/l) XOi (-) | ; | ; | Uric acid (μmol/l) XOi (+) | ; NS | ; NS | Bilirubin (μmol/l) | ; | ; | Albumin (g/l) | ; | ; |
| | VO2 maks. | VO2 maks. | PSH (μmol/g of protein) | ; NS | ; | TAC (mmol/l) | ; NS | ; NS | TOS (mmol/l) | ; NS | ; NS | OSI (TOS/TAC) | ; NS | ; NS | MDA (μmol/l) | ; | ; | MDA/PSH ratio | ; | ; | Uric acid (μmol/l) (all) | ; | ; NS | Uric acid (μmol/l) XOi (-) | ; | ; NS | Uric acid (μmol/l) XOi (+) | ; NS | ; NS | Bilirubin (μmol/l) | ; | ; | Albumin (g/l) | ; | ; |
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ICM: ischaemic cardiomyopathy; nICM: nonischaemic cardiomyopathy; NYHA: New York Heart Association functional class; LVEF: left ventricle ejection fraction; NT-proBNP: N-terminal pro-B-type natriuretic peptide; VO2max: maximum oxygen output; TAC: total antioxidant capacity; TOS: total oxidant status; OSI: oxidative stress index; MDA: malondialdehyde; PSH: sulfhydryl groups; XOi: xanthine oxidase inhibitors.
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