Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 5

Research Article

Multiorgan Development of Oxidative and Nitrosative Stress in LPS-Induced Endotoxemia in C57Bl/6 Mice: DHE-Based In Vivo Approach

Figure 5

Eicosanoid concentration in plasma in a murine model of endotoxemia, 6 and 12 hours after LPS challenge. PGE2 (a), TXB2 (b), and 12-HETE (c). Data are presented as or , and statistical significance was tested using one-way ANOVA post hoc LSD’s test or Kruskal-Wallis, post hoc Dunn’s (for b, c), depending on the distribution and homoscedasticity of data. values <0.05 were considered significant, with <0.05, <0.01, and <0.001 versus the control group, and ○ <0.05 and ○○ <0.01 versus the LPS 6 h group.

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