Oxidative Medicine and Cellular Longevity / 2019 / Article / Tab 1

Research Article

Multiorgan Development of Oxidative and Nitrosative Stress in LPS-Induced Endotoxemia in C57Bl/6 Mice: DHE-Based In Vivo Approach

Table 1

DHE, 2-OH-E+, and E+ detected in tissues after injection of DHE (i.v.) in a murine model of endotoxemia, 6 and 12 hours after LPS challenge.

TissueControlLPS 6 hLPS 12 h

DHE (pg/mg protein)Liver () () ()
Lung () () ()
Kidney<LOD<LOD<LOD
Brain<LOD<LOD<LOD

2-OH-E+ (pg/mg protein)Liver () () ()
Lung () () ()
Kidney () () ()
Brain< LOD ()0.31 ()

E+ (pg/mg protein)Liver () () ()
Lung () () ()
Kidney () () ()
Brain () () ()

Data are presented as . Results of Student’s-test vs. control (in bold):, , , and .

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