Research Article

High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells

Figure 1

High LDL decreases NOS3 protein levels. Human primary endothelial cells were cultured in the standard medium (con) or medium containing 1 mg/ml LDL (high LDL) for 7 days. Full-length NOS3 protein was detected by immunoblot; ERK1/2 served as a loading control. (a) Representative immunoblots. (b) Semiquantitative analysis. Data are ; ; vs. con.
(a)
(b)