High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells

Table 1

Relative NOS3 exon-exon junction expression. Comparison of relative expression of all exon-exon junctions from exon 1 to exon 18 (1 : 18), exon 18 to exon 27 (18 : 27), and exon-exon junctions indicative of alternative splicing from exon 14 onto exons 14A/B/C (14-14x) or skipping exon 21 (20-22). The exon-exon junction coverage was normalized per sample to the number of gapped reads within the sample and to gene expression; the value was calculated with Student’s -test. Exon-exon junctions indicative of skipping exon 20 or exon 20 and 21 simultaneously were not detectable.

Exon-exon junction	Average normalized expression		value
	con	High LDL
1 : 18	3,740	3,153	0.00
18:27	3,949	4,876	0.02
14-14x	0.009	0.010	0.83
20-22	0.002	0.024	0.16