Evidence of Blood and Muscle Redox Status Imbalance in Experimentally Induced Renal Insufficiency in a Rabbit Model
Table 3
Psoas and soleus muscle biochemical and redox status indices in the control and uremic groups.
Psoas muscle
Soleus muscle
Control group ()≠
95% confidence interval
Uremic group ()≠
95% confidence interval
Control group ()≠
95% confidence interval
Uremic group ()≠
95% confidence interval
Lower bound
Upper bound
Lower bound
Upper bound
Lower bound
Upper bound
Lower bound
Upper bound
Total protein (mg/ml)
4.865
6.642
3.836
5.240
†
2.161
4.148
2.588
3.992
GSH (μmol/g protein)
2.014
9.065
3.300
8.875
4.155
12.039
8.625
14.20
GSSG (μmol/g protein)
0.060
0.470
0.160
0.484
0.102
0.560
0.310
0.634
Ratio (GSH/GSSG)
-4.455
41.775
7.326
43.874
20.782
72.468
15.34
51.89
GR (U/g protein)
5.912
15.273
9.018
16.419
13.184
23.651
12.724
20.125
TAC (μmol DPPH/ml)
0.458
0.732
0.411
0.627
0.169
0.476
0.155
0.372
CAT (U/mg protein)
-2.799
16.785
-2.020
13.463
18.140
40.063
#
15.863
31.346
TBARS (nmol/ml)
0.983
5.376
0.561
4.034
4.350
9.262
4.511
7.984
Data are presented as . Confidence intervals are reported. TBARS: thiobarbituric acid reactive substances; GSH: reduced glutathione; GSSG: glutathione oxidized; TAC: total antioxidant capacity; CAT: catalase. †Statistical significance between control psoas and control soleus, #statistical significance between uremic psoas and uremic soleus, .≠It should be noted that muscle analysis refers to for the control and for the uremic group as a batch of samples became inappropriate for analysis.
