Research Article
CD28 Deficiency Ameliorates Thoracic Blast Exposure-Induced Oxidative Stress and Apoptosis in the Brain through the PI3K/Nrf2/Keap1 Signaling Pathway
Figure 1
Inflammation and expression of CD28 increased in the lung after blast thoracic exposure. (a) Histopathological changes of the lung in C57BL/6 mice and CD28−/− mice after blast thoracic exposure. The arrows point to the inflammatory region. (b) The expression of CD28 in the lung in C57BL/6 mice after blast thoracic exposure. (c) Relative density of CD28. (d) Western blot of CD28 in C57BL/6 mice and CD28-/- mice. (e–g) The concentration of inflammatory factors detected in the serum by ELISA. Data are the . compared with the control group; , compared with the control group; #, compared with C57BL/6 mice in the same time point; ##, compared with C57BL/6 mice in the same time point.
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