Research Article

[Retracted] Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway

Table 4

Effects of grape seed proanthocyanidin extract on primary methylation index and secondary methylation index in Nrf2-suppressed cells.

GSPE (mg/L)Nrf2 normal cellsNrf2-suppressed cells
0500102550

PMIMean2.125.061.802.713.454.40
SD0.250.400.220.200.280.32

SMIMean32.2255.2831.0247.6349.4351.63#
SD1.100.420.440.880.400.15

Versus the GSPE (0 mg/L) group, ; #versus the same intervention group in Nrf2 normal cells, .