Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 4

Research Article

Euphorbia bicolor (Euphorbiaceae) Latex Extract Reduces Inflammatory Cytokines and Oxidative Stress in a Rat Model of Orofacial Pain

Figure 4

E. bicolor latex extract reduces ROS levels in both male and female rats. CFA inflammation (closed bar) increased ROS levels in the trigeminal ganglia of male (a) and female (b) rats as compared to saline treatment (diagonal bar). compared to vehicle by the Student -test analysis. ROS levels decreased in the trigeminal ganglia of males (c) at 6 and 24 hours and females (d) at 72 hours post E. bicolor latex extract injection (closed bars) as compared to vehicle treatment (open bars). Dotted lines indicate the ROS level in noninflamed rats. compared to vehicle by two-way ANOVA with Bonferroni post hoc analysis.
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