Overexpression of BRCA1 in Neural Stem Cells Enhances Cell Survival and Functional Recovery after Transplantation into Experimental Ischemic Stroke

<div>Overexpression of BRCA1 reduced NSCs apoptosis after OGD/R. NSCs were transfected with LV-GFP or LV-BRCA1 before OGD administration. (a) TUNEL-AP staining and PI/Hoechst 333342 double staining were performed to detect cell apoptosis 24 h after reoxygenation. (b) Quantification of PI-positive NSCs. OGD/R administration increased apoptosis of NSCs, which was attenuated by LV-BRCA1 transfection. 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Scale bar: 50 <i>μ</i>m.</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Overexpression of BRCA1 in Neural Stem Cells Enhances Cell Survival and Functional Recovery after Transplantation into Experimental Ischemic Stroke 

Figure 2 | Overexpression of BRCA1 in Neural Stem Cells Enhances Cell Survival and Functional Recovery after Transplantation into Experimental Ischemic Stroke 