Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling

Figure 2

Effects of SAC on serum AST (a), ALT (b), T-Bil (c), TC (d), and TG (e) in APAP-induced mice. Mice were given PBS and SAC (20 mg/kg) alone or SAC (5, 10, and 20 mg/kg body weight) via intraperitoneal injection 1 h before challenge with APAP (400 mg/kg). Mice were killed at 12 h after APAP challenge. The values are reported as the .E.M. of six mice per group. compared with the control group; , , and compared with the APAP group.

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