Research Article

[Retracted] Yiqi-Huoxue Granule (YQHX) Downregulates Prothrombotic Factors by Modulating KLF2 and NF-κB in HUVECs following LPS Stimulation

Figure 4

YQHX inhibits the PAI-1 and TF expression in a KLF2-dependent manner. (a) HUVECs were infected with Lenti-GFP or Lenti-shKLF2 for 24 h. (b) HUVECs were infected with Lenti-GFP or Lenti-shKLF2. Then, they were incubated with YQHX (1.25 mg/ml) for 3 h prior to 25 μg/ml LPS stimulation for 12 h. Cell lysates were prepared and subjected to Western blot measurements to determine the expression of KLF2, PAI-1, and TF. Data are expressed as (). vs. control, vs. group with 25 μg/ml LPS or LPS plus Lenti-GFP, and vs. LPS plus YQHX or LPS plus YQHX and Lenti-GFP.
(a)
(b)