Antioxidant and Cardioprotective Effects of EPA on Early Low-Severity Sepsis through UCP3 and SIRT3 Upholding of the Mitochondrial Redox Potential

Figure 5

Myocardial hypoxia-inducible factor-1 (HIF-1) (a) and sirtuin-3 (SIRT3) (b) mRNA expressions. The means are the average of 8 rats. DEF: rats fed the ω3 polyunsaturated fatty acid-deficient diet; EPA: rats fed the eicosapentaenoic acid-enriched diet; Sham: sham-operated rats; Sept: septic rats; : diet effect; : sepsis effect; A, B: histogram bars on the same panel without a common letter are significantly different.

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