Antioxidant and Cardioprotective Effects of EPA on Early Low-Severity Sepsis through UCP3 and SIRT3 Upholding of the Mitochondrial Redox Potential

Table 6

Glycolytic enzyme mRNA expressions in the myocardium.

	DEF Sham	DEF Sept	EPA Sham	EPA Sept	ANOVA
HK2					: CI:
PFK2					:
PKm					: :
LDHM					:
LDHH					: CI:
PDK4					:

The means represent the average of 8 rats. DEF Sham: rats fed the ω3 fatty acid-deficient diet with fictitious surgery; DEF Sept: rats fed the ω3 fatty acid-deficient diet with cecal ligation and puncture; EPA Sham: rats fed the EPA-rich diet with fictitious surgery; EPA Sept: animals fed the EPA-rich diet with the cecal ligation and puncture; HK2: hexokinase 2; PFK2: phosphofructokinase 2 inhibiting the phosphofructokinase 1; PKm: pyruvate kinase muscle type; LDHM: muscular lactate dehydrogenase catalyzing the transformation of pyruvate to lactate; LDHH: cardiac lactate dehydrogenase catalyzing the transformation of lactate to pyruvate; PDK4: pyruvate dehydrogenase kinase 4 inhibiting the pyruvate dehydrogenase by phosphorylation; ANOVA: analysis of variance. The two-way analysis of variance describes the effects of the diets (), those of sepsis (), and the cross-interaction between these two factors (CI); a, b, c: means without a common letter for the same parameter are significantly different.