Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma
OOS inhibits GBM growth. GBM1-3 cells were injected subcutaneously into the flanks of nude mice; when tumors became visible, animals started receiving daily oral doses of OOS (100 μl/day, 5 days/week) or water (control). Relative tumor growth at different time points (a) or the time of sacrifice (b) is represented, . (c) Representative pictures of the tumors are shown. (d) NESTIN expression (qRT-PCR) in flank tumors after OOS treatment, .RPII was used for normalization in all qRT-PCRs. ..
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