Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma
OOS inhibits intracranial tumor growth. GBM1 cells were injected into the brains of nude mice. The animals were treated orally with daily doses of OOS (200 μl, 5 days/week) or water (control). (a) Animal survival was evaluated using a Kaplan-Meier survival curve and the differences in survival times were analyzed with a log-rank test, . (b) qRT-PCR analysis of human β-tubulin (human TUB) related to RPII (human and mouse) levels in the dissected brains. Each bar represents one tumor. (c) Percentage of CD44+ cells in dissociated brain tumors analyzed by flow cytometry, ..
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.