Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 3

Research Article

Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma

Figure 3

OOS inhibits intracranial tumor growth. GBM1 cells were injected into the brains of nude mice. The animals were treated orally with daily doses of OOS (200 μl, 5 days/week) or water (control). (a) Animal survival was evaluated using a Kaplan-Meier survival curve and the differences in survival times were analyzed with a log-rank test, . (b) qRT-PCR analysis of human β-tubulin (human TUB) related to RPII (human and mouse) levels in the dissected brains. Each bar represents one tumor. (c) Percentage of CD44+ cells in dissociated brain tumors analyzed by flow cytometry, . .

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