Research Article

Fasting Whole-Body Energy Homeostasis and Hepatic Energy Metabolism in Nondiabetic Humans with Fatty Liver

Table 2

Whole-body energy metabolism as assessed by indirect calorimetry and high-energy phosphate hepatic relative content as assessed by 31P MRS.

Fatty liverControls value

Indirect calorimetry
 REE (Kcal/die)0.64
 % of predicted REE (%)0.25
 Respiratory quotient0.93
 Glucose oxidation (mg/(kg min))0.83
 Lipid oxidation (mg/(kg min))0.58
Hepatic 31P-MRS
 % PME0.48
 % Pi0.94
 % PDE0.72
 % γ-ATP0.50
 % α-ATP0.10
 % β-ATP0.47
 % ATP0.49
 Pi/γ-ATP ratio0.83
 Pi/ATP ratio0.63
 PME/Pi ratio0.56
 PME/γ-ATP ratio0.79
 PME/ATP ratio0.36

The peak area of each metabolite (PME, Pi, PDE, γ-ATP, α-ATP, and β-ATP) was expressed as a percentage of the total 31P-MR signal (the sum of all the resonances). ; independent-samples -test (2-tailed). REE: resting energy expenditure.