Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling

<div>Schematic illustration of experimental protocols used to explore the compromised cardioprotection of remifentanil preconditioning (RPC) in diabetes in <i>in vivo</i> (a) and <i>in vitro</i> (b) studies. I/R: ischemia/reperfusion; Wort: wortmannin; AG: AG490.</div>

Oxidative Medicine and Cellular Longevity

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Figure 1

Figure 1: Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling 

Figure 1 | Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling 