Oxidative Stress Markers Differ in Two Placental Dysfunction Pathologies: Pregnancy-Induced Hypertension and Intrauterine Growth Restriction
Table 4
Median and interquartile range of the entire study population.
PIH
IUGR
Controls
Plasma GPx (U/ml)
29.9 (11)a
29.1 (8.6)a
28.8 (7.8)a
Plasma GST (U/ml)
29.8 (6.0)a
27.8 (9.5)a
28 (8.0)a
Plasma ORAC (mM)
17 (16)ab
20 (30)a
12 (13)b
Plasma MDA (μM)
1.2 (1.3)ab
1.22 (0.84)a
1.53 (0.70)b
Salivary ALDH1 (U/g)
0.24 (0.40)a
0.34 (1.1)b
0.24 (0.36)a
Saliva ORAC (mM)
1.8 (2.6)ab
4.2 (4.1)a
1.5 (1.5)b
Blood ALDH1 (mU/g Hb)
7.1 (3.2)b
2.3 (5.9)a
4.7 (4.7)b
Saliva MDA (μM)
0.32 (0.21)a
0.29 (0.34) a
0.34 (0.18)a
abcHomogenous group according to the Kruskal Wallis test. 1Salivary ALDH and blood ALDH are different isoforms of the aldehyde dehydrogenase (i.e., isoforms 3 and 1, respectively) with different substrate specificities.