Irvingia gabonensis Seed Extract: An Effective Attenuator of Doxorubicin-Mediated Cardiotoxicity in Wistar Rats

Table 7

Antioxidant enzyme activities of 100-400 mg/kg/day of IGESE in DOX-treated rat cardiac tissue.

Groups	Antioxidant parameters
	GSH	GST	GPx	SOD	CAT	MDA
I
II
III
IV
V
VI
VII

^b+ represents a significant increase at when compared to untreated negative (normal) control (Group I) values; ^c+ represents a significant increase at when compared to IGESE-only treated (Group II) values; ^a-,b-, and^c- represent significant decreases at , , and , respectively, when compared to Groups I values; ^d+ and ^e+ represent significant increases at and , respectively, when compared to untreated positive control (DOX-only treated, Group III) values; while ^e- and ^f- represent significant decreases at and , respectively, when compared to untreated positive control (DOX-treated only, Group III) values, respectively. ^{d, e,} and ^f represent significant increases at , , and , respectively, when compared to untreated positive control (DOX-treated only, Group III).