IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer

<div>The overexpression of SLC7A11 rescues IMCA-induced CRC cell ferroptosis <i>in vitro</i>. Overexpression of SLC7A11 restored the decrease of Cys and glutathione content, the increase of ROS, and the decrease of cell viability induced by IMCA in DLD-1 (a) and HCT116 (b) cells.</div>

Oxidative Medicine and Cellular Longevity

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Figure 5

Figure 5: IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer 