Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide/Streptozotocin-Induced Wistar Diabetic Rats

Table 6

Serum AST and ALT activities in normal, diabetic control, and diabetic groups treated with C. reticulata fruit peel extract, hesperidin, and quercetin.

Parameter groups	AST (U/l)	% change	ALT (U/l)	% change
Normal	127.83 ± 2.22^c	—	25.15 ± 1.14^c	—
Diabetic control	193.33 ± 2.98^a	51.23%	46.36 ± 1.45^a	84.33%
Diabetic treated with fruit peel extract	148 ± 1.90^b	-23.44%	31.00 ± 1.36^b	-33.13%
Diabetic treated with hesperidin	131.5 ± 2.20^b	-31.98%	33.06 ± 1.66^b	-28.68%
Diabetic treated with quercetin	141.9 ± 3.16^b	-26.60%	31.63 ± 1.42^b	-31.77%
-probability
LSD at 5% level	8.98		5.15
LSD at 1% level	12.15		6.97

Data are represented as of six rats. Means which have different superscript letters are significantly different at . Percentage changes were calculated by comparing diabetic control with normal and diabetic treated groups with diabetic control.