Investigation of Cytotoxicity Apoptotic and Inflammatory Responses of Biosynthesized Zinc Oxide Nanoparticles from Ocimum sanctum Linn in Human Skin Keratinocyte (Hacat) and Human Lung Epithelial (A549) Cells
ZnNPs induce apoptosis and inflammatory response of HaCaT and A549 cells. Western blot analysis was carried out to assess apoptosis and inflammatory response-related protein expression in HaCaT and A549 cells. β-Actin was used as an internal reference. ZnNPs significantly increased the expression of Bax, caspase-3, and TNF-α and decreased the expression of Bcl-2 at a concentration 35 μg/ml (a, b). Data represents the of three experiments. and vs. control.
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