Oxidative Medicine and Cellular Longevity / 2020 / Article / Fig 7

Research Article

Investigation of Cytotoxicity Apoptotic and Inflammatory Responses of Biosynthesized Zinc Oxide Nanoparticles from Ocimum sanctum Linn in Human Skin Keratinocyte (Hacat) and Human Lung Epithelial (A549) Cells

Figure 7

ZnNPs induce apoptosis and inflammatory response of HaCaT and A549 cells. mRNA expression analysis was carried out to assess apoptosis and inflammatory response-related gene expression in HaCaT cells (a) and A549 cells (b). β-Actin was used as an internal reference. ZnNPs significantly increased the gene expression of Bax, caspase-3, and TNF-α and decreased the expression of Bcl-2 in a concentration-dependent manner (a, b). Data represents the of three experiments. and vs. control.

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