Inhibition of ERRα Aggravates Sepsis-Induced Acute Lung Injury in Rats via Provoking Inflammation and Oxidative Stress
Inhibition of ERRα aggravated CLP-induced lung injury and lung vascular hyperpermeability. (a) ERRα expression levels in the four groups. Representative blots (upper panel); Quantitative results (lower panel). (b) The lung tissues were histologically analyzed by hematoxylin and eosin in different groups (×200). (c) Lung injury was assessed by histological scores for each group. (d) Comparison of lung vascular Evans blue leakage in different groups. The values are expressed as .a compared with the Ctr and Sham group; b compared with the Sepsis group.
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