Research Article

Wenxin Keli Regulates Mitochondrial Oxidative Stress and Homeostasis and Improves Atrial Remodeling in Diabetic Rats

Table 1

Baseline characteristics and serum biochemical and oxidative stress parameters of rats in the three groups.

Control group ()DM group ()DM+WXKL group () value

Weight (g)0.012
Heart weight ratio (1/1000)0.009
Blood glucose (mmol/L)<0.001
IVS (mm)0.337
LVPW (mm)0.213
ratio0.823
Insulin (pmol/L)0.006
hs-CRP (mg/L)0.017
SOD (U/mL)#0.030
MDA (nmol/L)##<0.001
BUN (mmol/L)0.324
Cr (μmol/L)0.724
HDL-c (mmol/L)0.567
LDL-c (mmol/L)0.275
TC (mmol/L)0.003
TG (mmol/L)0.012

Values are expressed as . DM = diabetes mellitus; WXKL = Wenxin Keli; IVS = interventricular septum; LVPW = left ventricular posterior wall; hs-CRP = high-sensitivity C-reactive protein; SOD = superoxide dismutase; MDA = malondialdehyde; BUN = blood urea nitrogen; Cr = creatinine; HDL-c = high-density lipoprotein cholesterol; LDL-c = low-density lipoprotein cholesterol; TC = cholesterol; TG = triglyceride. Compared with the control group, . Compared with the control group, . #Compared with the DM group, ##Compared with the DM group, .