Research Article

Resveratrol Inhibits Ischemia-Induced Myocardial Senescence Signals and NLRP3 Inflammasome Activation

Figure 5

RSV inhibited cell apoptosis in mouse heart after MI. (a) TUNEL staining showing cardiac apoptosis after MI surgery (3 days after MI). (b) Quantitative analysis of TUNEL-positive (+) cells in infarction area. (c) Quantitative analysis of TUNEL-positive (+) cells in border zone of infarction area, five separate fields were calculated independently from 6 samples per group. (b, d) Representative blots and relative expression level of c-caspase 3 and Bax in the mouse heart (). Mouse hearts were harvested at the 3th day after MI surgery. Two-way ANOVA was used for significance examination. Data are presented as the . vs. the NS group, # vs. the MI+NS group.