Resveratrol Inhibits Ischemia-Induced Myocardial Senescence Signals and NLRP3 Inflammasome Activation
RSV inhibited cell apoptosis in mouse heart after MI. (a) TUNEL staining showing cardiac apoptosis after MI surgery (3 days after MI). (b) Quantitative analysis of TUNEL-positive (+) cells in infarction area. (c) Quantitative analysis of TUNEL-positive (+) cells in border zone of infarction area, five separate fields were calculated independently from 6 samples per group. (b, d) Representative blots and relative expression level of c-caspase 3 and Bax in the mouse heart (). Mouse hearts were harvested at the 3th day after MI surgery. Two-way ANOVA was used for significance examination. Data are presented as the . vs. the NS group, # vs. the MI+NS group.