Relationship between Oxidative Stress Biomarkers and Visual Field Progression in Patients with Primary Angle Closure Glaucoma

Table 1

Demographics and clinical characteristics.

Variable	Control group ()	PACG group ()	value
Age (year)			0.437^&
Gender (male/female)	34/55	37/57	0.872
BMI (m^2/kg)			0.348^&
SBP (mm Hg)			0.306^&
DBP (mm Hg)			0.589^&
Smoking (yes/no)	20/69	23/71	0.750
Drinking (yes/no)	22/67	24/70	0.899
Number of topical glaucoma medications,
0	—	4	—
1-2	—	33	—
>2	—	57	—
IOP (mm Hg)			<0.001^&
VCDR	—		—
CCT (mm)	—		—
ACD (cm)	—		—
AL (cm)	—		—
MD (dB)	—		—
MS (dB)	—		—
GPX (U/L)			0.517^&
GR (U/L)			0.148^&
SOD (U/mL)			<0.001^&
TAS			<0.001^&
MDA (umol/l)			<0.001^&
H2O2 (umol/l)			<0.001^&

^&Independent-samples -test; ^#Mann-Whitney test; test. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; IOP: intraocular pressure; VCDR: vertical cup-disc ratio; CCT: central corneal thickness; ACD: anterior chamber depth; AL: axial length; MD: visual field mean deviation; MS: visual field mean sensitivity; SOD: superoxide dismutase; TAS: total antioxidant status; H₂O₂: hydrogen peroxide; MDA: malondialdehyde; GPX: glutathione peroxidase; GR: glutathione reductase.