Isokotomolide A from Cinnamomum kotoense Induce Melanoma Autophagy and Apoptosis In Vivo and In Vitro

Table 1

The antioxidant activity assays of Iso A and Sec A.

	DPPH radical scavenging ability (%)				Metal chelating activity (%)				Reducing power (OD700)
Compounds (μM)	10	50	100	200	10	50	100	200	10	50	100	200
Iso A	≦5.0	≦5.0	≦10.0	≦15.0	≦5.0	≦5.0	≦10.0	≦15.0
Sec A	≦5.0	≦5.0	≦10.0		≦5.0	≦5.0	≦10.0	≦15.0
Vitamin C^a	—	—		—	—	—	—	—	—	—	—	—
EDTA^b	—	—	—	—	—	—		—	—	—	—	—
BHA ^c	—	—	—	—	—	—	—	—	—	—		—

^aVitamin C was the positive control of DPPH radical scavenging capacity assay with concentration at 100 μM; ^bEDTA was the positive control of metal chelating activity assay with concentration of at μM; ^cBHA was the positive control of reducing power assay with concentration at 100 μM.