Oxidative Medicine and Cellular Longevity / 2020 / Article / Tab 1

Research Article

Anethole Dithiolethione Increases Glutathione in Kidney by Inhibiting γ-Glutamyltranspeptidase: Biochemical Interpretation and Pharmacological Consequences

Table 1

Plasma thiols and disulfides in rats orally treated with ADT. Rats () were orally administered 1 mg/kg (b.w.) saline () or ADT () once a day. After 1 week, 2 weeks, or 3 weeks, low molecular mass thiols, low molecular mass disulfides, and S-thiolated proteins were measured in plasma ( for each group). Data are expressed as μM. vs. vehicle group; vs. vehicle group.

Thiol1 week2 weeks3 weeks
Vehicle groupADT groupVehicle groupADT groupVehicle groupADT group

GSH
GSSG
GSSP
CysGly
CySSGly
CyGlySSP
Cys
CySS
CySSP
Hcys
HcySS
HcySSP

Abbreviations: GSH: glutathione; GSSG: glutathione disulfide; GSSP: protein mixed disulfides with GSH; CysGly: cysteinylglycine; CySSGly: cysteinylglycine; CyGlySSP: protein mixed disulfides with CysGly; Cys: cysteine; CySS: cystine; CySSP: protein mixed disulfides with Cys; Hcys: homocysteine; HcySS: homocysteine, HcySSP: protein mixed disulfides with Hcys.

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