Research Article

Cerebral Mitochondrial Function and Cognitive Performance during Aging: A Longitudinal Study in NMRI Mice

Table 3

Basal ATP and MMP levels of dissociated brain cells (DBCs) as well as protein-normalized respiration of complexes I and IV in isolated mitochondria from 3-, 12-, 18-, and 24-month-old mice; ; ; with one-way ANOVA and Tukey’s post hoc test with , , and compared to young control animals. # indicates significant changes against 18-month-old mice with .

ATP level (nmol/mg protein)MMP level (AU/mg protein)CI (pmol/(smg protein))CIV (pmol/(smg protein))

3 mo
6 mo
12 mo
18 mo
24 mo#