Research Article

Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway

Figure 3

ERS is involved in I/R injury. (a) The effects of I/R and DZ treatment on protein expressions of GRP78, IRE1, and XBP1 were detected using Western blot. (b) Histogram summarizing results in (a). (c) The effects of the miR-10a mimic, miR-10a inhibitor, and DZ treatment separately or simultaneously on protein expressions of GRP78, IRE1, and XBP1 were detected using Western blot. (d) Histogram summarizing results in (c). Data were expressed as in three independent experiments. and , compared to the NC group.
(a)
(b)
(c)
(d)