Research Article

Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway

Figure 5

Regulation of ERS by miR-10a in cardiomyocytes. (a) The effect of the miR-10a inhibitor and knockdown IRE1 on expression of GRP78 was detected by immunofluorescence. . (b) Fluorescence intensity of each group in (a). (c) The effect of the miR-10a inhibitor and knockdown IRE1 on cell viability of each group was detected by MTT analysis. (d) The effect of the miR-10a inhibitor and knockdown IRE1 on LDH release of each group was detected by LDH analysis. Data were expressed as in three independent experiments. and , compared to the NC group.
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