Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway
Regulation of ERS by the miR-10a inhibitor in rat myocardial tissue. (a) The schematic diagram of the established myocardial I/R injury rat model and injected AAV. (b) qRT-PCR was used to detect the miR-10a and IRE1 expression. (c) Rat myocardial tissues in different groups were detected by HE staining. . (d) The effects of the miR-10a inhibitor on protein expressions of GRP78, IRE1, and XBP1 were detected using Western blot. (e) Histogram summarizing results in (d). Data were expressed as (). and , compared to the NC group.