Protective Effect of Astragaloside IV on High Glucose-Induced Endothelial Dysfunction via Inhibition of P2X7R Dependent P38 MAPK Signaling Pathway

Figure 6

Effect of As-IV and SB203580 on inflammation and oxidative stress induced by high glucose in RAOEC. (a–e) IL-6, TNF-α, IL-1β, and IL-18 proteins, and GSH-px activity were measured by ELISA (). (f) The level of SOD in RAOEC was measured using a SOD assay kit (). (g, h) The level of ROS was determined by DHE dye (). DHE dye (red). vs. control group. ^## vs. HG group.

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