Oxidative Medicine and Cellular Longevity

Research Article

Increased Serum Levels of IFN-γ, IL-1β, and IL-6 in Patients with Alopecia Areata and Nonsegmental Vitiligo

Table 3

The correlation between serum levels of interferon γ (IFN-γ), interleukin- (IL-) 1β, and IL-6 (pg/ml) and extent, activity, and duration of the disease among patients with alopecia areata (AA) and patients with nonsegmental vitiligo (NSV).


Correlation between serum cytokine levels and	Alopecia areata (AA)			Nonsegmental vitiligo (NSV)
Correlation between serum cytokine levels and	Extent of AA (SALT)	Activity of AA (VIDA)	Duration of AA	Extent of NSV (VASI)	Activity of NSV (VIDA)	Duration of NSV

IFN-γ (q in the Spearman test/ value)	-0.055/0.759218	-0.206/0.250208	-0.150/0.421353	-0.055/0.778851	-0.148/0.444011	-0.137/0.478715
IL-1β ( in the Spearman test/ value)	0.038/0.833562	0.181/0.314325	-0.073/0.694889	0.383/0.040441	-0.435/0.018387	0.458/0.012573
IL-6 ( in trhe Spearman test/ value)	0.116/0.520565	-0.050/0.784260	0.453/0.010474	-0.054/0.779845	-0,190/0.323085	0,222/0,247687

SALT: Severity of Alopecia Tool score; VIDA: Vitiligo Disease Activity Score; VASI: Vitiligo Area Severity Index; IL: interleukin; IFN: interferon.