A Dihydroflavonoid Naringin Extends the Lifespan of C. elegans and Delays the Progression of Aging-Related Diseases in PD/AD Models via DAF-16

Figure 7

Naringin could not extend the lifespan of long-lived mutants in the nutrition-sensing pathway. (a–d) Survival curves of eat-2, sir2.1, rsks-1,and clk-1 mutants in the control or treated with 50 μM naringin; naringin could not further extend the mean lifespan of C. elegans. Statistical details and repeats of these experiments are summarized in Table S1 (Supplementary information).

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