Research Article

EGCG Attenuates Renal Damage via Reversing Klotho Hypermethylation in Diabetic db/db Mice and HK-2 Cells

Figure 5

The protein expression of Klotho, DNMT1, DNMT3a, and DNMT3b in HK-2 cells detected by western blotting. (a and b) The protein expression of Klotho. (c–e) The protein expression of Klotho, DNMT1, DNMT3a, and DNMT3b. NG: normal glucose (5.5 mM); HG: high glucose (60 mM); EGCG: HK-2 cells treated with 1 μM EGCG. Values are expressed as . vs. the HG group; vs. the HG group.
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