EGCG Attenuates Renal Damage via Reversing Klotho Hypermethylation in Diabetic db/db Mice and HK-2 Cells

Figure 8

Schematic representation of the underlying mechanisms by which EGCG regulates HG-induced oxidative stress, inflammation, and renal fibrosis. (a–d) The expression of oxidative stress, inflammation, and renal fibrosis markers under normal, HG, HG+EGCG, and HG+EGCG+Klotho KO conditions.

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