Research Article

Effect of Antioxidants on the Fibroblast Replicative Lifespan In Vitro

Table 1

Fibroblast lines used in RLS studies.

FibroblastsOriginReferences

2BSHuman fetal lung diploid fibroblasts human, female[58]
FB0603Human diploid foreskin fibroblasts[47]
H8F2p 25LM fibroblastsIsolated from human ear[73]
HDFsHuman dermal fibroblasts[8, 56, 6062, 74]
HE49Human embryonic fibroblasts, normal[37]
HEFsHuman embryonic fibroblasts, established from an abortus[35]
HFF1 (ATCC® SCRC1041™)Human foreskin, from a newborn male[48, 66]
HFL1 (ATCC® CCL-153™)Isolated from human fetal lungs, Caucasian[57]
HGPSNormal human skin fibroblast[72]
Hs68 (ATCC® CRL-1635™)Human skin (foreskin), from a newborn male, Caucasian[46]
IMR-90 (ATCC® CCL-186™)Human lung, female, 16 weeks of gestation, Caucasian[12, 22, 30, 71]
MRC-5 (ATCC® CCL-171™)Human lung, 14 weeks of gestation fetus, male, Caucasian[44, 66, 75]
Normal diploid fibroblastsIsolated from foreskin[25, 26, 59]
Normal human skin fibroblasts[64]
NYaKeNormal human adult fibroblasts derived from a 23-year-old healthy male[27]
Primary cultures of human dermal fibroblastsFemale[65]
WI-38 (ATCC® CCL-75™)Human fetal lung diploid fibroblasts, 3 months of gestation fetus, female, Caucasian[33, 34, 54, 55, 58, 76]
WS3RGBFibroblasts obtained from a 42-year-old female Werner syndrome patient[37]