Oxidative Medicine and Cellular Longevity

Research Article

Ameliorating Effect of Klotho Protein on Rat Heart during I/R Injury

Table 1

An influence of Klotho on cardiac mechanical function of isolated rat hearts.


Parameter	Aero	Aero+Klotho	I/R	I/R+Klotho

dP/dt_max (mmHg/s)^†
PED (mmHg)^†
LVDP (mmHg)^†				^#
RPP ()^†				^#
CF (mL/min)^‡				^#

CF: coronary flow; dP/dt_max: baseline left ventricular maximal contractility; I/R: ischaemia/reperfusion; LVDP: left ventricular developed pressure; PED: left ventricular end-diastolic pressure; RPP: rate pressure product; ;; ; ; ; vs. Aero; ^# vs. I/R; ANOVA. ^†After I/R (77 min of the experiment); ^‡after ischaemia (first minute of reperfusion).