RiPerC Attenuates Cerebral Ischemia Injury through Regulation of miR-98/PIK3IP1/PI3K/AKT Signaling Pathway

Figure 2

PIK3IP1 3-UTR was directly targeted by miR-98. (a) Schema of the WT and mutated PIK3IP1 3-UTR indicating the interaction sites between miR-98 and the 3-UTR of PIK3IP1. (b) Dual luciferase assay in HEK293T cells cotransfected with the miR-98 mimic and reporter vectors containing either the wild-type or mutated 3-UTR of PIK3IP1. (c) The miR-98 in rats hippocampus tissue detected by qPCR. (d) The miR-98 in rats cerebral cortex tissue detected by qPCR.

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