Vagus Nerve Stimulation Ameliorates Renal Ischemia-Reperfusion Injury through Inhibiting NF-κB Activation and iNOS Protein Expression

Figure 5

VNS decreases NF-κB activation and reduces iNOS expression in the kidney. (a) Representative relative protein expression of NF-κB p65 and iNOS in different groups. (b) The relative protein levels of NF-κB in renal tissues are shown. (c, d) The level of iNOS mRNA and iNOS protein expression from the renal tissues in different groups. (e–f) The levels of nitrate/nitrite and 3-NT formation from the renal tissues in different groups. Data are expressed as with per group. versus the sham group; ^# versus the I/R group. iNOS: inducible nitric oxide synthase; 3-NT: 3-nitrotyrosine.

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