MG53 Protects against Sepsis-Induced Myocardial Dysfunction by Upregulating Peroxisome Proliferator-Activated Receptor-α

Figure 2

Myocardial MG53 and PPARα decreased in SIMD rats. Supplementation of MG53 improved PPARα expression. (a) Representative western blot bands of MG53 and PPARα at 3 h, 6 h, 12 h, 18 h, and 24 h after CLP in experiment 1. Densitometric analysis of the (b) MG53 and (c) PPARα protein levels in experiment 1. (d) Representative western blot bands of MG53 and PPARα at 18 h after CLP in experiment 2. Densitometric analysis of the (e) MG53 and (f) PPARα protein levels in experiment 2. Data are presented as , . , , and . CLP = cecal ligation and puncture; rhMG53 = recombinant human MG53.

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