Research Article

Investigation of the Role of Oxidative Stress and Factors Associated with Cardiac Allograft Vasculopathy in Patients after Heart Transplantation

Table 3

A summary of the receiver operating characteristic curve analysis for TAC, TOS, and OSI.

AUC (±95 CI)Cut-offSensitivity (±95 CI)Specificity (±95 CI)PPV (±95 CI)NPV (±95 CI)LR+ (±95 CI)LR- (±95 CI)Accuracy

TAC0.8940 (0.8515-0.9365)<0.0011.080.74 (0.64-0.83)0.85 (0.76-0.91)0.83 (0.73-0.90)0.77 (0.67-0.84)4.8 (2.48-7.12)0.30 (0.20-0.41)0.79 (0.73-0.85)
TOS0.8620 (0.8126-0.9114)<0.0014.940.65 (0.55-0.74)0.90 (0.82-0.95)0.86 (0.76-0.93)0.72 (0.63-0.80)6.30 (2.46-10.14)0.39 (0.28-0.50)0.77 (0.71-0.83)
OSI0.9530 (0.9279-0.9781)<0.0014.170.89 (0.81-0.94)0.87 (0.78-0.93)0.87 (0.79-0.93)0.88 (0.80-0.94)6,62 (3.21-10.02)0.13 (0.06-0.20)0.88 (0.82-0.92)

Abbreviations: AUC: area under the curve; CI: confidence interval; LR-: negative likelihood ratio; LR+: positive likelihood ratio; NPV: negative predictive value; OSI: oxidative stress index; PPV: positive predictive value; TAC: total antioxidant capacity; TOS: total oxidant status.