Research Article

Bu-Shen-Yi-Sui Capsule, an Herbal Medicine Formula, Promotes Remyelination by Modulating the Molecular Signals via Exosomes in Mice with Experimental Autoimmune Encephalomyelitis

Table 1

Major GO categories regulated by 16 differentially expressed (DE) miRs in serum exosomes.

CategoryTermInvolved in

Biological processGO:0045664Regulation of neuron differentiation72<0.001
GO:0071363Cellular response to growth factor stimulus57<0.001
GO:0030334Regulation of cell migration74<0.001
GO:0043087Regulation of GTPase activity64<0.001
GO:0007409Axonogenesis45<0.001

Molecular functionGO:0005543Phospholipid binding45<0.001
GO:0051020GTPase binding31<0.001
GO:0005102Receptor binding101<0.001
GO:0019904Protein domain specific binding54<0.001
GO:0019838Growth factor binding18<0.001

Cellular componentGO:0097458Neuron part118<0.001
GO:0045202Synapse80<0.001
GO:0005856Cytoskeleton157<0.001
GO:0030054Cell junction103<0.001
GO:0030424Axon44<0.001