Despite Blocking Doxorubicin-Induced Vascular Damage, Quercetin Ameliorates Its Antibreast Cancer Activity

<div>The effect of quercetin on the cytotoxicity of DOX in MCF-7 (a), MDA-MB231 (b), and T47D (c) cell lines. Cells were exposed to serial dilution of DOX (●), quercetin (○), or DOX+Que combination (▼) for 72 h. Cell viability was determined using SRB assay. The intracellular/total concentrations of ROS were determined using CMFDA fluorescent dye after 1 h (d) and 24 h (e, f) of exposure to DOX, quercetin, their combination, and TBHP as a positive control. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Despite Blocking Doxorubicin-Induced Vascular Damage, Quercetin Ameliorates Its Antibreast Cancer Activity 