| | Reference | Plant preparation, dose, way and time of treatment, animals | The dose and negative effects | Protective effects of plant preparation | Effects of plant per se |
| | Dong et al. [70] | Spatholobus suberectus Dunn (Ji-Xue-Teng Beijing Lvye Pharmaceutical Co. Ltd., China) 75% ethanol extract
40 g/kg, p.o., for 21 consecutive days after irradiation
Chinese Kun Ming (KM) mice, 6–8 week aged | 60Co γ-radiation, a dose of 6 Gy
Body weight: ↓
Blood: WBC, RBC, PLT, HGB ↓
Bone marrow tissue: Bcl-2 expression, phosphorylation of JAK2 and STAT5a ↓
Liver: ROS, MDA↑, SOD, GPx ↓
Femur: bone marrow cells ↓ | Body weight: (+++)
Blood: WBC, PLT, HGB (++), RBC (+++)
Bone marrow tissue: phosphorylation of JAK2 (++), phosphorylation of STAT5a and Bcl-2 expression (+++)
Liver: ROS, MDA (++), SOD, GPx (+++)
Femur: bone marrow cells (++) | Not studied |
| | Jeena et al. [145] | Zingiber officinale R (ginger) essential oil (Kancore Ingredients Limited, Angamali, Kerala, India)
100 or 500 mg/kg b.w. p.o., 5-day pretreatment and then for 14 days
Male Balb/C mice, 6-8 week | γ-Radiation, 6 Gy, whole body exposure
Blood: WBC, HGB ↓
Intestinal mucosa: SOD, CAT, GPx, GSH ↓ | Blood: WBC (++), HGB (+++)
Intestinal mucosa: SOD CAT, GPx and GSH (++ 100, +++ 500) | Not studied |
| | Khattab et al. [146] | Borago officinalis L. seeds oil
Posttreatment: 50 mg/kg b.w./day, p.o., 3 hours after irradiation and for 2 weeks
Pretreatment: 50 mg/kg b.w./day, p.o., one week before irradiation and for 2 weeks
Male albino rats, 160-180 g | γ-Radiation
a single sublethal dose of 6.5 Gy of whole body
Serum: GSH, HDL-c ↓, AST, ALT, GGT, MDA, TG, TC, LDL-c ↑
Liver: GSH ↓, MDA ↑ | Posttreatment:
Serum: AST, ALT (++), GGT, MDA, TG, TC, GSH, LDL-c, HDL-c (+++)
Liver: GSH (++), MDA (+++)
Pretreatment:
Serum: AST, ALT (++), GGT, MDA, TG, TC, GSH, LDL-c, HDL-c (+++)
Liver: GSH (++), MDA (+++) | None |
| | Wang et al. [147] | Rubus idaeus red raspberry ethanolic extract
750 μg/mL applied on the dorsal region of the nude mice 1 day before UVB and then for 5 days
Female nude mice (ICR-Foxn/nu strain) | UVB 30 mJ/cm2 in the dorsal region, once a day for 5 days
Total dose of 150 mJ/cm2 per mouse
Skin epidermal thickness: ↑
Transepidermal water loss ↑
Erythema ↑
Skin: COX-2, DNA oxidation and protein carbonylation ↑ | Skin epidermal thickness: (+++)
Transepidermal water loss (++)
Erythema (++)
Skin: COX-2, DNA oxidation (++), protein carbonylation (+++) | Not studied |
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