Research Article

Differential Gender-Dependent Patterns of Cardiac Fibrosis and Fibroblast Phenotypes in Aging Mice

Figure 5

Non-epicardial origin of cardiac fibroblasts in the young and aged hearts. (a-c) Perivascular coronary, epicardial and myocardial immunofluorescence staining (488 nm) for Tcf21, Tbx18 and Wt1 of histological sections obtained from young and aged mice of both sexes. Nuclei are stained blue with DAPI. White asterisks indicate coronary vessels. Scale bars: 50 μm. Magnifications: x200. animals per group, fields of view per condition. vs young male and female, vs aged female or male.
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